This is the only [Star Trek] series to have the same regular cast throughout its entire run.
John ShibanJohn Shiban, who previously had a long career on the [The X Files], was brought on as writer and producer of [Enterprise] for its second season. The first episode he wrote was #2.3, {Minefield}, and tackled a sensitive subject in the world of Trek continuity, the Romulans. Despite fears, the episode was raved by critics and fans accepted the complicated continuity as a result.
The first [Star Trek] series to not use "starring" and "also starring" in the credits; also the first to not name the characters being played by the actors (i.e. [Actor] as [Character]).
After the space shuttle Columbia disaster on 1 February 2003, last-minute editing on episode #2.17, {Canamar}, (broadcast 26 February 2003) was done to remove a shot of a spaceship exploding as it enters a planet's atmosphere.
The solar system in the title sequence is described in German.
Jeffrey CombsJeffrey Combs, Gary GrahamGary Graham and Matt WinstonMatt Winston are the only actors, besides the regulars, to appear in all four seasons.
The interiors were inspired by a visit to a docked nuclear submarine.
The bridge set has 80 plasma screens built into it.